Model NO.: CZG-SARM06
Product Name: Aicar
CAS No.: 2627-69-2
Model No: Czg-Sarm06
Mf: C9h14n4o5
MW: 258.23
Appearance: Powder
Place of Origin: China
Export Markets: Global
Brand Name: Czg
Forms: Pills, Powder, Liquid
Trademark: CL, CZG
Transport Package: Professional Packing with Professional Materials
Specification: USP, ISO9001
Origin: Jiangsu, China(Mainland)
HS Code: 2937290090
Model NO.: CZG-SARM06
Product Name: Aicar
CAS No.: 2627-69-2
Model No: Czg-Sarm06
Mf: C9h14n4o5
MW: 258.23
Appearance: Powder
Place of Origin: China
Export Markets: Global
Brand Name: Czg
Forms: Pills, Powder, Liquid
Trademark: CL, CZG
Transport Package: Professional Packing with Professional Materials
Specification: USP, ISO9001
Origin: Jiangsu, China(Mainland)
HS Code: 2937290090
99% Purity Bodybuilding Powder Sarms CAS 2627-69-2 Aicar Â
Product Name:Aicar
Aicar CAS:2627-69-2
Aicar Mf:C9h14n4o5
Aicar MW:258.23
Aicar Einecs:220-097-5
Aicar Appearance:Powder
Aicar Purity:99%Â Min.Â
MK 677
Aicar Specification:
Item |
Specification |
Result |
| Appearance |
White powder |
Complies |
| Related substance (HPLC) |
Total impurity ≤0.5%
Max single impurity ≤0.1% |
0.2%
0.06% |
| Odor |
Characteristic |
Complies |
| Assay |
99% |
99.8% |
| Sieve analysis |
100% pass 80 mesh |
Complies |
Loss on Drying
Residue on Ignition |
≤1.0%
≤1.0% |
0.12%
0.09% |
| Heavy Metal |
<10ppm |
Complies |
| As |
<0.1ppm |
0.05ppm |
| Pb |
<0.1ppm |
0.05ppm |
| Cd |
<0.1ppm |
0.05ppm |
| Residual Solvents |
<100ppm |
Complies |
| Residual Pesticide |
Negative |
Complies |
| Microbiology |
 |
 |
| Total Plate Count |
<1000cfu/g |
Complies |
| Yeast & Mold |
<100cfu/g |
Complies |
| E.Coli |
Negative |
Complies |
| Salmonella |
Negative |
Complies |
Â
ACADESINE;AICAR;AICA-RIBOSIDE;AMPK;5-AMINOIMIDAZOLE-4-CARBOXAMIDE-1-BETA-RIBOSIDE;5-AMINOIMIDAZOLE-4-CARBOXAMIDE-1-B-D-RIBOFURANOSIDE;5-AMINOIMIDAZOLE-4-CARBOXAMIDEÂ 1-BETA-D-RIBOFURANOSIDE;Z-RIBOSIDEÂ
CAS:Â 2627-69-2 Â
Aicar Introductions:AICAR is a peptide whose technical name is 5-Aminoimidazole-4-carboxamide ribonucleotide. It can also be known as AICA ribonucleotide, ZMP, or Acadesine. It is an intermediate contained in the generation of inosine monophosphate. It primarily functions as an AMP-activated protein kinase agonist, meaning that it has the ability to promote the operation of nutrient stores for energy production. It has a molecular mass of 338.211, and it has a molecular formula of C9H15N4O8P.
AICAR is an adenosine analog that selectively activates AMP-activated protein kinase (AMPK). AMPK regulates lipid and glucose metabolism to maintain cellular energy homeostasis (Hardie and Carling).
AICAR can play a hand in boosting these processes because it contains the ability to penetrate cardiac cells and block the production of enzymes tied to regulating glucose intake and energy expulsion. With these regulatory enzymes inhibited, the affected cells can in turn boost the amount of glucose that can be received, and it can also increase its level of energy conversion. Additionally, the peptide's presence has been determined to aid in lowering programmed cell death, a process that is also known as apoptosis.
Functions:
AICAR (AICA-Riboside) strongly inhibits the transcription of PPAR&alpha and the coactivation of PPAR&alpha. In adipocyte studies it has been shown to antagonize lipolysis induced by isoprenaline and has been suggested for use in kinase cascade research. Additionally, research indicates that AICAR blocks the differentiation of 3T3-L1 (sc-2243) adipocytes. Studies demonstrate that AICAR can mimic the activity of insulins (sc-211647) by activating AMPK (AMP-activated protein kinase), and affecting the expression of PEPCK-M (PEPCK) and glucose-6-phosphatase (G6Pase). The 5-aminoimidazole-4-carboxamide ribonucleoside (ZMP) is the monophosphorylated derivative of AICA-Riboside, and it can serve as the substrate for the aminoimidazole carboxamide ribonucleotide transformylase/inosine monophosphate cyclohydrolase (ATIC). AICAR is an inhibitor of Hsp90, mTOR and p70 S6 Kinase.
AMP-activated protein kinase (AMPK) functions as a metabolic sensor that regulates lipid and glucose metabolism to maintain cellular energy homeostasis and to protect against metabolic stress.AICAR is a selective activator of AMPK in both hepatocytes and adipocytes. At 0.5 mM it inhibits the synthesis of fatty acids and sterols and inactivates HMG-CoA reductase in rat hepatocytes.AICAR (0.5 mM) inhibits insulins-stimulated glucose uptake to 62% of controls and reduces GLUT4 translocation 2.5-fold in 3T3-L1 adipocytes. It also blocks the expression of pro-inflammatory cytokines (TNF-α/IL-1β and IL-6), iNOS, COX-2, and MnSOD genes in glial cells and macrophages by inhibiting NFκB and C/EBP pathways.Biological Activity:
AICAR is a cell permeable activator of AMP-activated protein kinase (AMPK), a metabolic master regulator that is activated in times of reduced energy availability (high cellular AMP:ATP ratios) and serves to inhibit anabolic processes. In vivo, pharmacologic activation of AMPK with AICAR mimics exercise and triggers insulins-independent glucose uptake by skeletal muscle.
Cell-permeable, allosteric activator of AMP-activated protein kinase (AMPK). Augments proliferation, differentiation and mineralization of osteoblastic MC3T3-EI cells and attenuates psychosine-induced expression of proinflammatory cytokines and iNOS in astrocytes. Promotes osteogenic differentiation of hAMSCs and BM-MSCsin vitro. Payment method: Escrow, Western Union, Paypal, TT, L/C.
Shipping method: Fedex, DHL, EMS or by SEA
Delivery time: within 3days after payment, 7-10days to arrive.
Our process:1) Contact me about what you need and your quantity, we will quoted you details.
2) Finish the payment.
3) We will arrange to send parcel out within 3days after payment, when tracking number updates, we will   email you.
4) Parcel delivered.
Â
After-sales service:1.We will ship the goods within 3days after get your payments.If you want to cancelÂ
or change order, please tell me within 24hours after you finish the payment...So we both can make theÂ
best of the bad bargain.
2.We will ship the goods that you order from us by EMS, DHL, UPS, or FedEx.We will decided to chooseÂ
which courier depend on Different countries.To find the best way to delivery the goods for you.
3.As usual you can get the goods with in 4-7days.
If the goods were lost or not received for other reasons, please contact me Immediately.
Factory price, pure injection, best credit.
Â
Offical website: http://www.czgpharmacy.com/.
Â
Contact method:Miss. Sherry Wang
Tel:Â +86-18861110306
   +86 0519 86879655
Fax:+86Â 0519Â 86474295
You are welcome to inquiry any time!More products:Â
| Name |
CAS |
| Ostarine,MK-2866,Enobosarm |
1202044-20-9 |
| Ibutamoren Mesylate,MK-677 |
159752-10-0 |
| LGD-4033 |
1165910-22-4 |
| Andarine(S4) |
401900-40-1 |
| Cardarine,GW-501516 |
317318-70-0 |
| AICAR |
2627-69-2 |
| SR9009 |
1379686-30-2 |
| RAD140 |
1182367-47-0 |
Â
SR9009Â
Â
99% Purity Bodybuilding Powder Sarms CAS 2627-69-2 Aicar Â
Product Name:Aicar
Aicar CAS:2627-69-2
Aicar Mf:C9h14n4o5
Aicar MW:258.23
Aicar Einecs:220-097-5
Aicar Appearance:Powder
Aicar Purity:99%Â Min.Â
MK 677Aicar Specification:
Item |
Specification |
Result |
| Appearance |
White powder |
Complies |
| Related substance (HPLC) |
Total impurity ≤0.5%
Max single impurity ≤0.1% |
0.2%
0.06% |
| Odor |
Characteristic |
Complies |
| Assay |
99% |
99.8% |
| Sieve analysis |
100% pass 80 mesh |
Complies |
Loss on Drying
Residue on Ignition |
≤1.0%
≤1.0% |
0.12%
0.09% |
| Heavy Metal |
<10ppm |
Complies |
| As |
<0.1ppm |
0.05ppm |
| Pb |
<0.1ppm |
0.05ppm |
| Cd |
<0.1ppm |
0.05ppm |
| Residual Solvents |
<100ppm |
Complies |
| Residual Pesticide |
Negative |
Complies |
| Microbiology |
 |
 |
| Total Plate Count |
<1000cfu/g |
Complies |
| Yeast & Mold |
<100cfu/g |
Complies |
| E.Coli |
Negative |
Complies |
| Salmonella |
Negative |
Complies |
Â
ACADESINE;AICAR;AICA-RIBOSIDE;AMPK;5-AMINOIMIDAZOLE-4-CARBOXAMIDE-1-BETA-RIBOSIDE;5-AMINOIMIDAZOLE-4-CARBOXAMIDE-1-B-D-RIBOFURANOSIDE;5-AMINOIMIDAZOLE-4-CARBOXAMIDEÂ 1-BETA-D-RIBOFURANOSIDE;Z-RIBOSIDEÂ
CAS:Â 2627-69-2 Â
Aicar Introductions:AICAR is a peptide whose technical name is 5-Aminoimidazole-4-carboxamide ribonucleotide. It can also be known as AICA ribonucleotide, ZMP, or Acadesine. It is an intermediate contained in the generation of inosine monophosphate. It primarily functions as an AMP-activated protein kinase agonist, meaning that it has the ability to promote the operation of nutrient stores for energy production. It has a molecular mass of 338.211, and it has a molecular formula of C9H15N4O8P.
AICAR is an adenosine analog that selectively activates AMP-activated protein kinase (AMPK). AMPK regulates lipid and glucose metabolism to maintain cellular energy homeostasis (Hardie and Carling).
AICAR can play a hand in boosting these processes because it contains the ability to penetrate cardiac cells and block the production of enzymes tied to regulating glucose intake and energy expulsion. With these regulatory enzymes inhibited, the affected cells can in turn boost the amount of glucose that can be received, and it can also increase its level of energy conversion. Additionally, the peptide's presence has been determined to aid in lowering programmed cell death, a process that is also known as apoptosis.
Functions:
AICAR (AICA-Riboside) strongly inhibits the transcription of PPAR&alpha and the coactivation of PPAR&alpha. In adipocyte studies it has been shown to antagonize lipolysis induced by isoprenaline and has been suggested for use in kinase cascade research. Additionally, research indicates that AICAR blocks the differentiation of 3T3-L1 (sc-2243) adipocytes. Studies demonstrate that AICAR can mimic the activity of insulins (sc-211647) by activating AMPK (AMP-activated protein kinase), and affecting the expression of PEPCK-M (PEPCK) and glucose-6-phosphatase (G6Pase). The 5-aminoimidazole-4-carboxamide ribonucleoside (ZMP) is the monophosphorylated derivative of AICA-Riboside, and it can serve as the substrate for the aminoimidazole carboxamide ribonucleotide transformylase/inosine monophosphate cyclohydrolase (ATIC). AICAR is an inhibitor of Hsp90, mTOR and p70 S6 Kinase.
AMP-activated protein kinase (AMPK) functions as a metabolic sensor that regulates lipid and glucose metabolism to maintain cellular energy homeostasis and to protect against metabolic stress.AICAR is a selective activator of AMPK in both hepatocytes and adipocytes. At 0.5 mM it inhibits the synthesis of fatty acids and sterols and inactivates HMG-CoA reductase in rat hepatocytes.AICAR (0.5 mM) inhibits insulins-stimulated glucose uptake to 62% of controls and reduces GLUT4 translocation 2.5-fold in 3T3-L1 adipocytes. It also blocks the expression of pro-inflammatory cytokines (TNF-α/IL-1β and IL-6), iNOS, COX-2, and MnSOD genes in glial cells and macrophages by inhibiting NFκB and C/EBP pathways.Biological Activity:
AICAR is a cell permeable activator of AMP-activated protein kinase (AMPK), a metabolic master regulator that is activated in times of reduced energy availability (high cellular AMP:ATP ratios) and serves to inhibit anabolic processes. In vivo, pharmacologic activation of AMPK with AICAR mimics exercise and triggers insulins-independent glucose uptake by skeletal muscle.
Cell-permeable, allosteric activator of AMP-activated protein kinase (AMPK). Augments proliferation, differentiation and mineralization of osteoblastic MC3T3-EI cells and attenuates psychosine-induced expression of proinflammatory cytokines and iNOS in astrocytes. Promotes osteogenic differentiation of hAMSCs and BM-MSCsin vitro. Payment method: Escrow, Western Union, Paypal, TT, L/C.
Shipping method: Fedex, DHL, EMS or by SEA
Delivery time: within 3days after payment, 7-10days to arrive.
Our process:1) Contact me about what you need and your quantity, we will quoted you details.
2) Finish the payment.
3) We will arrange to send parcel out within 3days after payment, when tracking number updates, we will   email you.
4) Parcel delivered.
Â
After-sales service:1.We will ship the goods within 3days after get your payments.If you want to cancelÂ
or change order, please tell me within 24hours after you finish the payment...So we both can make theÂ
best of the bad bargain.
2.We will ship the goods that you order from us by EMS, DHL, UPS, or FedEx.We will decided to chooseÂ
which courier depend on Different countries.To find the best way to delivery the goods for you.
3.As usual you can get the goods with in 4-7days.
If the goods were lost or not received for other reasons, please contact me Immediately.
Factory price, pure injection, best credit.
Â
Offical website: http://www.czgpharmacy.com/.
Â
Contact method:Miss. Sherry Wang
Tel:Â +86-18861110306
   +86 0519 86879655
Fax:+86Â 0519Â 86474295
You are welcome to inquiry any time!More products:Â
| Name |
CAS |
| Ostarine,MK-2866,Enobosarm |
1202044-20-9 |
| Ibutamoren Mesylate,MK-677 |
159752-10-0 |
| LGD-4033 |
1165910-22-4 |
| Andarine(S4) |
401900-40-1 |
| Cardarine,GW-501516 |
317318-70-0 |
| AICAR |
2627-69-2 |
| SR9009 |
1379686-30-2 |
| RAD140 |
1182367-47-0 |
Â
SR9009Â
Â