Tablets can not be opened casually. Sustained-release tablets must be swallowed.
Active Pharmaceutical Ingredients Active Pharmaceutical Ingredients(API) refer to the raw materials used in the production of various preparations. They are the effective ingredients in the preparations. They are various powders, crystals, extracts, etc., prepared by chemical synthesis, plant extraction or biotechnology, but Substances that the patient cannot take directly. API is intended to be used in any substance or mixture of substances in the manufacture of pharmaceuticals, and when used in pharmaceuticals, it becomes an active ingredient of the pharmaceuticals. Such substances have pharmacological activity or other direct effects in the diagnosis, treatment, symptom relief, treatment or prevention of diseases, or can affect the function or structure of the body. According to its source, active pharmaceutical ingredients are divided into two categories: synthetic chemical active Pharmaceutical ingredients and natural chemical active Pharmaceutical ingredients. Chromium Picolinate,Tianeptine,6-Paradol,Aminobutyric acid,acetylcysteine,L-Carnosine Xi'an Gawen Biotechnology Co., Ltd , https://www.ahualynbio.com
How can I tell if the tablets can be opened?
1. Read the instructions. If the instructions in the manual list the use of half a tablet, then go for it; if there are hints in the instructions, such as "small swallow", "not open or crush", you can only eat the whole piece.
2. Observe whether there are any nicks on the surface of the tablet. The nicks themselves are designed to pry the tablets neatly, so the scored tablets can be taken along the nicks.
3. Judging according to the nature of pharmacy.
Ordinary tablets are directly compressed with processed drugs and excipients. There is no special structure, just like inside and outside. In this tablet, the dissolution rate of the whole piece and the half piece is basically the same, so it can be eaten open.
Sugar-coated tablets and ordinary film-coated tablets can also be opened, because they are coated with a film on the surface, but this film dissolves in the digestive tract in a short time, and there is no restriction on drug release. The dissolution rate of the whole piece and the half piece is not much different, and it is basically no problem to open it.
But beware, the same is the coating, the enteric coating can be completely different. If the generic name of a drug reads “XX enteric-coated tabletsâ€, it means that the outer bread of this tablet has a special enteric material – this material is insoluble in the acidic gastric juice, but waits until the tablet reaches the pH bias. The neutral intestines began to dissolve, and the drugs inside began to be released.
Why can't I take pills?
There are two purposes for making drugs into enteric-coated tablets: one is to protect the drug from decomposition by gastric acid; the other is to protect the stomach from drug stimulation. Therefore, if the enteric coated tablet is opened, the protective barrier will be destroyed, and the above-mentioned purpose will not be achieved, resulting in a decrease in the efficacy of the drug or an upset or even ulceration of the stomach. Therefore, enteric-coated tablets are unacceptable.
Some pills have a more complex structure, which is a sustained release tablet and a controlled release tablet. In order to release the drug slowly and smoothly, both tablets use a special tablet structure, including both membrane type and skeleton type.
Membrane-type tablets are coated with a film that can limit the slow release of the drug. The film is forcibly broken to destroy the film, and the drug-containing core is directly exposed, and the drug is quickly released. As a result, the amount of drug entering the body in a short time will greatly exceed the expectation, so that the safety of the drug cannot be guaranteed. And in this way, the drug can no longer be effective for a long time. Therefore, the controlled release sheet of the membrane type structure cannot be opened.
The drug in the skeleton type tablet is dispersed in a mesh composed of a skeleton material, just like the soil retained by the root of the plant. Such tablets control drug release through many fine pores in the matrix material or by slow dissolution of the matrix material itself.
Therefore, even if the tablets are split in half, the drugs can still be released slowly. Therefore, the slow-release tablets of the skeleton structure can be opened and eaten.