Clostridium cloacae detection is expected to diagnose early colorectal cancer
Recently, the 8th Shanghai International Conference on Gastroenterology was held. Chinese and foreign experts from all over the world stressed that intestinal micro-ecology will become a new target for early diagnosis and treatment of colorectal cancer. Prof. Fang Jingyuan, deputy dean of Shanghai Renji Hospital, director of the Department of Gastroenterology and director of the Institute of Digestive Diseases, pointed out that the high-cost and low-cost detection of Clostridium commensii is expected to become a new non-invasive method for early diagnosis of colorectal cancer. Fang Jingyuan introduced that after comprehensive analysis of existing and international big data sequencing results, the team successfully found a new class of intestinal colonization bacteria, the symbiotic Clostridium, associated with the development of early colorectal. And through the multi-center large sample clinical data, it is proved that symbiotic Clostridium is a highly effective early biomarker for colorectal cancer, and its diagnostic efficiency for early colorectal cancer is higher than that of conventional fecal occult blood and serum tumor markers. The corresponding methods and means are independently designed and developed by the team, and applied for national invention patents. At present, relevant clinical transformation issues are being actively implemented. In recent years, many research data have confirmed the relationship between intestinal flora and colorectal tumors. Fang Jingyuan, for example, E. coli is a cofactor for colorectal cancer, and the number of E. coli is closely related to the clinical stage of colorectal cancer patients. Therefore, intestinal micro-ecology composed of pathogenic Escherichia coli and the like may be used for screening of colorectal cancer. (Special correspondent Yuan Wei) Shanghai J.Shine Co.,Ltd , https://www.jshinechem.com