Male smoking affects cognitive ability of offspring
Male smoking affects cognitive ability of offspring October 23, 2018 Source: Science and Technology Daily Author: Liu Haiying Researchers at Florida State University published a study in the latest issue of the Journal of Public Science Libraries and Biology, saying that a mouse model study showed that exposure of male mice to nicotine leads to their children and grandchildren. A cognitive deficit has occurred. The researchers believe that the results of this study are equally applicable to humans. They warn those who want to be parents and pay more attention to the dangers of smoking. Smoking is harmful to human health, regardless of gender, but people tend to pay more attention to smoking problems in pregnant women because they know that smoking in pregnant women can harm their children's health. Although the proportion of male smokers is much higher than that of females, the impact of male smoking on offspring has not received widespread attention, and little is known about such risks. This time, Florida State University researchers used the influence of male smoking on offspring as a research goal. They used mice as a research object to analyze the spontaneous movement, working memory, attention and anti-reverse learning ability of children and grandchildren of male mice exposed to nicotine (zero generation mice). The results showed that the spontaneous motor behavior of the children of the zero generation mice (first generation mice) increased significantly, while the reverse learning ability decreased significantly. Male generation mice also showed significant defects in attention, brain monoamine content, and dopamine receptor mRNA (microRNA) expression. The test results of the children of the first generation mice (second generation mice) showed that the reverse learning ability of the second generation male mice produced by the first generation of female mice was significantly defective. The researchers analyzed the epigenetic changes in spermatozoa from zero-generation mice. The results showed that exposure to nicotine caused multiple epigenetic changes in the genes in mouse sperm, including the dopamine D2 receptor gene promoter. DNA methylation in the region. The dopamine D2 gene plays an important role in the development of brain development and cognitive ability. Researchers believe that this is likely to be the reason why smoking harm is intergenerational and affects the cognitive ability of offspring. The researchers pointed out that although the study was done in mice, previous studies on the effects of maternal nicotine exposure, whether in mice or in human females and children, have been consistent. Therefore, there is reason to believe that the results of this mouse study are equally applicable to humans, and people should pay more attention to the public health problem of smoking. Jewelry Safes,Jewelry Safe,Best Jewelry Safe,Jewelry Safe Box Hebei Yingbo Safe Boxes Co.,Ltd , https://www.yingbosafebox.com