Russian scientists use optogenetics to repair blind eye neurons
Release date: 2018-06-14 Vision is produced by a specific neuron located on the retina of the eye responding to light and signaling the brain. When the neurons stop working properly, the eyes become blind. RIA Novosti recently announced that Russian scientists have developed a drug that restores vision in the laboratory, allowing patients blinded by loss of light sensitivity to the retina to see the light again. As early as 1999, British biologists, physicists, and neuroscientists (1962 Nobel Prize in Physiology or Medicine) Francis Crick proposed the idea of ​​embedding light-sensitive proteins into neurons and achieving light control. Six years later, optogenetics was born, and scientists began to clone genes that make light-sensitive proteins. In 2017, a team of researchers from the Moscow University, the Institute of Bioorganic Chemistry of the Russian Academy of Sciences and the Institute of Advanced Neurological and Neurophysiology of the Russian Academy of Sciences, began to work together to develop a drug that restores light sensitivity to the retina - able to A nucleotide sequence that is attached to the living cell genetic device and organizes the "factory" production of the light-sensitive protein. This genetic structure is capable of delivering an artificial virus to a designated location. Although artificial viruses cannot replicate themselves, they can pass through cells, but they cannot penetrate muscles and connective tissues. Scientists injected drugs with the above genetic structure into the blind eyes of experimental rodents. Two weeks later, the experimental mice began to distinguish between light and shadow, which means that the orientation can be determined, but objects and colors are not visible. With a single injection of the drug, vision can be partially restored, and its application prospects are very promising. According to reports, a person's dose is only 0.001 ml, a scientific laboratory can easily prepare the required dose of drugs. Therefore, the drug does not need to be put into mass production, which greatly simplifies the process of placing the market. The research team is clearly not satisfied with the results achieved, and has recently launched a new drug development and immediate animal (mouse) experimental program. For repeated trials of mice, repeated trials and clinical trials are still required. All of the above work will be completed between 2019 and 2020. Researchers say that the technology that is currently in place is on the verge of facing a scientific breakthrough. Source: China Medical Promotion Association Whether it's from sleeping weird, working out too hard, or sitting hunched over for hours staring at your computer, most of us have dealt with kinks in our necks from time to time. According to a peer-reviewed article from Marco Funiciello and Zinovy Meyler, Doctors of Osteopathic Medicine, one of the best ways to soothe aches and pains in your neck is through massage therapy. Deep Muscles Massager,3D Neck Massager,Electric Back Massagers,Heated Neck Massagers Ningbo Shuangtuo International Trade Co., Ltd. , https://www.nbst-sports.com
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