How to choose a centrifugal extractor suitable for the extraction process

According to the use, size and power of the centrifugal extractor, the user should select the appropriate centrifugal extractor according to the site used and the nature of the treated material to achieve the intended purpose.

There are five issues that must be considered when selecting a model:

1, size power

Common centrifugal extractors from the market, from small laboratory centrifugal extractors to huge industrial processing centrifugal extractors. Taking CWL-M as an example, its external dimensions range from a small 270*200*760mm to an industrialized 1500*1500*2500mm, while the power is from a small 0.18kw to a larger 37kw. Its use also varies with its size. Smaller centrifugal extractors are an excellent choice for laboratory applications, and the advantages of large-scale centrifugal extractors for industrial hydrometallurgy and traditional Chinese medicine extraction are particularly evident.

2, anti-corrosion performance

The materials separated by the centrifugal extractor generally have certain corrosiveness, and the material in contact with the material must have high corrosion resistance. Especially in the centrifugal extractor, the requirements for corrosion resistance and high temperature are high, and only the centrifugal extractor is Safe use is guaranteed during operation. The type of structural parts (304, 321 , 316L, titanium plate), sealing ring, gasket material, surface treatment measures (lining plastic, rubber lining, surface spraying halar), and the material of the filter cloth should be selected. When determined. The manufacturer can be informed of the nature of the material (chemical properties, temperature at the time of separation, etc.) at the time of selection so that the manufacturer can suggest the choice of centrifuge material based on the characteristics of the medium to be separated and indicate in the order to ensure The anti-corrosion requirements of the centrifuge.

3, explosion-proof performance

If the material (or environment) treated by the centrifugal extractor contains inflammable and explosive substances such as organic solvents, the centrifugal extractor should have explosion-proof performance. Explosion-proof performance is determined by the explosion-proof requirements (grade) of the process. In the explosion-proof occasions previously involved, only the explosion-proof motor was proposed. In the past two years, most of the cases where the treated materials contain organic solvents such as solvents have been proposed. In fact, the centrifugal extraction machine should realize the explosion-proof in the true sense, and take various measures in the aspects of mechanical, electronic control and accessory configuration. Such as:

1. Electronic control system: explosion-proof isolation barrier, non-contact energy-consuming braking system, electrostatic grounding, automatic explosion-proof control.

2. Mechanical system: explosion-proof motor, explosion-proof lighting, anti-collision measures, anti-static transmission belt.

3. Explosion-proof accessories: nitrogen protection device, nitrogen online detection, on-site explosion-proof control button.

Therefore, in the case of explosion-proof requirements, the user should specify the separated medium, explosion-proof requirements and grades when ordering, configure the corresponding equipment and take appropriate measures to meet the explosion-proof requirements.

4, structural aspects

The principle of the centrifugal extractor is a centrifuge that extracts two liquid phases of different densities of solvent and solvent to realize the extraction process of the solute in the solution to the solvent. Due to the internal automatic processing technology, its structure is limited by the installation method. Vertical, horizontal, inclined, overhang and three-legged according to the installation method. For the special requirements of the structure, it can be negotiated with the manufacturer at the beginning of the order to save time and effort in the future.

5. Environmental protection

For the current Chinese market, the purchase of centrifugal extractors is not only concerned with factors such as size, power, structure, corrosion protection and explosion protection. Another crucial factor is environmental protection. In recent years, centrifugal extraction machines have made considerable contributions to the production of pharmaceuticals. Due to the influence of the domestic pharmaceutical industry, centrifugal extraction machines must be effectively modified, which puts higher requirements on the production of centrifugal extraction machines. Under the premise of maintaining the separation characteristics of the centrifugal extractor, it is also necessary to meet the requirements of the "Good Manufacturing Practices", "General Rules for Pharmaceutical Equipment in Accordance with Good Manufacturing Practices" and "Guidelines for the Validation of Pharmaceutical Machinery (Equipment)". At the same time, the surface of the equipment directly in contact with the drug inside the centrifugal extractor should be smooth, flat, free of dead angles, easy to clean or have purification, sterilization, corrosion resistance, no chemical reaction with drugs or adsorption of drugs.

6, the price aspect

The difference between the domestic centrifugal extractor and the imported centrifugal extractor is not very large. The core technology of the centrifugal extractor has been mastered in China. The price difference between centrifuges of the same grade is not very large, mainly in terms of performance and configuration.

The difference between the mainframes is that in terms of performance, the centrifugal extractor with freezing is much more expensive than the ordinary ones, and some centrifugal extracting machines have heating functions. The more control programs, the higher the price of the centrifugal extractor. The big difference is the configuration aspect, and sometimes the price of the attachment is often higher than the price of the host. When purchasing, be careful to select the rotor (quantity and type), in addition to the main unit, plus the necessary centrifuge tubes, sleeves, special centrifuge bottles or blood bags, all of which add up to a complete centrifuge. price.

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