Nature: Heavyweight research will open the myth of human immortality
Aging, that is, as the body ages, the cell's ability to divide and grow is degraded. It can induce the deterioration of the body's function and age-related diseases. Anti-aging has always been a dream of human beings. However, for biologists, Finding substances that can effectively control the body's aging and clarifying the molecular mechanisms of aging can be not an easy task. Recently, a research report published in the international journal Nature Chemical Biology, researchers from the Daegu Gyeongbuk Institute of Science and Technology (DGIST) hope to study the aging process of the body, in order to reverse the aging process of the body, research The staff searched for multiple factors that could control aging, and the researchers also looked for substances that could restore the ability of cell sorting. Eventually they locked in a substance called KU-60019, which is an inhibitor of ATM protein, ATM protein. It is a phosphorylated enzyme that restores the function of senescent cells by activating the function of lysosomes and inducing cell proliferation. Lysosomes are intracellular organelles in cells that are responsible for autophagy and the breakdown of biopolymers (such as proteins and lipid molecules). Degradation of lysosomes induces cellular senescence, which is achieved by accumulation in cells. Removal of biomolecules and promotion of cellular metabolic instability, such as removal of dysfunctional mitochondria. Safety Pants
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