2016 IVD Big Four M&A Competition: Who wins Abbott, Roche, Danaher and Siemens?
In the second half of 2016, the IVD market was quite lively. First, in March, Thermo Fisher wanted to bid $30 billion for the sequencing giant Illumina; Danaher acquired Cepheid in September; then in October, Roche Diagnostics announced the completion of the full integration of the kapaNGS series; November Siemens acquired Conworx, and in early December, Abbott announced the termination of the acquisition of US Airil. Why does the in vitro diagnostic market move a lot? What is the current status of the four giants of IVD? According to Boston Biomedical Consultants, Inc., the global in vitro diagnostic (IVD) market will reach $68.9 billion in 2019; EvaluateMedTech estimates at the end of last year that the global medical device market will reach $477.5 billion in 2020, while IVD sales are expected to reach US$ US$67.3 billion (13%), the compound annual growth rate will reach 6.1% between 2015 and 2020, which is higher than the overall growth rate of 5% in the medical machinery industry in the same period. Regardless of which party's data, IVD is undoubtedly the territory of capital biting. Analysis of in vitro diagnostic classification The in vitro diagnostic (IVD) business is mainly divided into in vitro diagnostic reagents, in vitro diagnostic instruments and consumables. In China's IVD market, the reagent business accounts for about 80% of the total market share. There are many subdivisions in IVD, which can be divided into clinical laboratory diagnosis and immediate diagnosis (POCT) according to the use environment and operators. According to different indicators, specimens and principles, the “three countries†in the IVD market are biochemical diagnosis and immunity. Diagnosis and molecular diagnosis. Biochemical diagnosis started early, and it is the most common traditional examination in clinical practice. It mainly measures enzymes, lipids, proteins and non-protein nitrogens, and its technical barriers are low. The automatic biochemical analyzer is easy to operate, fast in detection, high in precision, good in repeatability, and the test result is not affected by operation. It is the development direction of biochemical detection. The immunodiagnosis is detected by antigen-antibody specific binding, and there are many kinds of reagents. The current mainstream technologies are enzyme-linked immunosorbent and chemiluminescence technologies. Among them, the chemiluminescence technology has a high degree of automation, and it is gradually replacing enzyme-linked immunoassay. The chemiluminescence technology has high barriers, and instruments and reagents must be used together. Therefore, the domestic high-end market is still occupied by foreign companies. The low-end market and hospitals with instrument replacement requirements may become a breakthrough for domestic manufacturers. Molecular diagnostics is the fastest growing sub-sector in the IVD industry (14% growth rate). The main technologies include nucleic acid amplification technology (PCR), in situ hybridization (ISH), gene sequencing , and gene chips.
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6.Application method:
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Dilution is necessary before used for the solid product. The normal dilution ratio for the solid product is 5%-15%.
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