British developed a new drug for sleeping sickness
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African sleeping sickness, commonly known as African trypanosomiasis, is transmitted by tsetse flies (Glossina). When the insect bites a human, it will inject the cone parasites into the body, infect the patient's brain, causing it to appear drowsiness symptoms, if not treated in time there will be life-threatening. However, the commonly used therapeutic drug, mela-arsenicol, has serious toxic and side effects due to arsenic, and the patient's mortality rate reaches 5% after use.
Researchers at the University of Glasgow and other institutions in the United Kingdom report that if you combine melatonin with another cyclodextrin, it can reduce its toxicity. Based on this research, the researchers developed a new drug. The experimental rats infected with sleeping sickness were cured after taking the new drug for one week, and no obvious side effects were found.
Another advantage of the new drug is that it can be made into oral tablets. In the past, the method of using alamon arsenol was intravenous injection, so the new drug is also convenient to use.